Figure S3.

Analysis of active and passive properties of human DRG sensory neurons, related to Fig. 5 . (A–D) Analysis of AP threshold (*P = 0.0232 for single versus delayed and ***P < 0.001 for delayed versus repeated), AP amplitude, AP overshoot, and AP rise (**P = 0.006 for delayed versus repeated) from all human sensory neurons. All data were analyzed from the control treatment (single: n = 9, black; delayed: n = 7, light grey; repeated: n = 20, dark grey). (E) Rheobase-ramp comparing responding neurons from control media (black, n = 32) versus KCl-treated cells (red, n = 24), P = 0.0558 using Mann-Whitney test. Statistical analysis was performed with one-way ANOVAs with Tukey’s multiple comparisons or Kruskal–Wallis test with Dunn’s multiple comparisons. Data are represented as mean ± SEM.