Appendix 1—table 2. k estimated from 12 cancer types.
| Cancer type | k |
|---|---|
| Breast | 5.05 |
| CNS | 2.59 |
| Endometrium | 5.49 |
| Kidney | 7.70 |
| Large intestine | 4.76 |
| Liver | 5.23 |
| Lung | 2.62 |
| Ovary | 4.30 |
| Prostate | 3.60 |
| Stomach | 4.17 |
| Upper-AD tract | 4.14 |
| Urinary tract | 6.14 |
| merged set* | 3.27 |
Note:- Estimation of k is derived from negative binomial regression, based on synonymous changes aggregated by the 3 bp local context at mutated sites across all coding genes. The estimation method is implemented in package dndscv.
*
The merged set contains mutation information from all 12 cancer types.