Abstract
Nucleolar changes of haemopoietic cells during the development of the mouse yolk sac blood islands were qualitatively examined by light and electron microscopy. Haemopoiesis in the yolk sac begins at seven days of gestation and, after the formation of vitelline vessels, erythropoiesis appears to be active at ten days. At 7-8 days of gestation, angioblasts have large and reticulated nucleoli in connection with the nuclear envelope either through the invagination of the nuclear membrane, i.e. canals and tubular or lamellar structures, or directly. The nucleoli of the fixed primitive erythroblasts at 8-9 days are of compound type and invaginations of the nuclear membrane are rarely seen. In free erythroblasts, fibrillary areas become obscure. In matured erythroblasts, remnants of the nucleoli are present in the heterochromatin masses. Nucleolar changes in each stage are so characteristic that nucleolar structure can be useful in the recognition of the differentiation stages of yolk sac haemopoetic cells.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Babai F., Tremblay G., Dumont A. Intranuclear and intranucleolar tubular structures in Novikoff hepatoma cells. J Ultrastruct Res. 1969 Jul;28(1):125–130. doi: 10.1016/s0022-5320(69)90010-0. [DOI] [PubMed] [Google Scholar]
- Bourgeois C. A., Hemon D., Bouteille M. Structural relationship between the nucleolus and the nuclear envelope. J Ultrastruct Res. 1979 Sep;68(3):328–340. doi: 10.1016/s0022-5320(79)90165-5. [DOI] [PubMed] [Google Scholar]
- Brinkley B. R. The fine structure of the nucleolus in mitotic divisions of Chinese hamster cells in vitro. J Cell Biol. 1965 Nov;27(2):411–422. doi: 10.1083/jcb.27.2.411. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Edmonds R. H. Electron microscopy of erythropoiesis in the avian yolk sac. Anat Rec. 1966 Apr;154(4):785–805. doi: 10.1002/ar.1091540408. [DOI] [PubMed] [Google Scholar]
- Fukuda T. Fetal hemopoiesis. I. Electron microscopic studies on human yolk sac hemopoiesis. Virchows Arch B Cell Pathol. 1973 Dec 7;14(3):197–213. [PubMed] [Google Scholar]
- GRASSO J. A., SWIFT H., ACKERMAN G. A. Observations on the development of erythrocytes in mammalian fetal liver. J Cell Biol. 1962 Aug;14:235–254. doi: 10.1083/jcb.14.2.235. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ghosh S. The nucleolar structure. Int Rev Cytol. 1976;44:1–28. doi: 10.1016/s0074-7696(08)61645-9. [DOI] [PubMed] [Google Scholar]
- Goessens G., Lepoint A. The fine structure of the nucleolus during interphase and mitosis in Ehrlich tumour cells cultivated in vitro. Exp Cell Res. 1974 Jul;87(1):63–72. doi: 10.1016/0014-4827(74)90527-8. [DOI] [PubMed] [Google Scholar]
- Haar J. L., Ackerman G. A. A phase and electron microscopic study of vasculogenesis and erythropoiesis in the yolk sac of the mouse. Anat Rec. 1971 Jun;170(2):199–223. doi: 10.1002/ar.1091700206. [DOI] [PubMed] [Google Scholar]
- Jollie W. P. Nuclear and cytoplasmic annulate lamellae in trophoblast giant cells of rat placenta. Anat Rec. 1969 Sep;165(1):1–13. doi: 10.1002/ar.1091650102. [DOI] [PubMed] [Google Scholar]
- Levine A. S., Nesbit M. E., White J. G., Yarbro J. W. Effects of fractionated histones on nucleic acid synthesis in 6C3HED mouse ascites tumor cells and in normal spleen cells. Cancer Res. 1968 May;28(5):831–844. [PubMed] [Google Scholar]
- More I. A., Armstrong E. M., McSeveney D., Chatfield W. R. The morphogenesis and fate of the nucleolar channel system in the human endometrial glandular cell. J Ultrastruct Res. 1974 Apr;47(20):74–85. doi: 10.1016/s0022-5320(74)90027-6. [DOI] [PubMed] [Google Scholar]
- Ollerich D. A., Carlson E. C. Ultrastructure of intranuclear annulate lamellae in giant cells of rat placenta. J Ultrastruct Res. 1970 Feb;30(3):411–422. doi: 10.1016/s0022-5320(70)80072-7. [DOI] [PubMed] [Google Scholar]
- Sasaki K., Matsumura G., Ito T. A quantitative morphology of nucleoli of erythroblasts in the mouse spleen: an electron microscopic study. Arch Histol Jpn. 1983 Feb;46(1):43–49. doi: 10.1679/aohc.46.43. [DOI] [PubMed] [Google Scholar]
- Sasaki K., Matsumura G., Ito T. Light and electron microscopy of bone marrow hemopoiesis in late embryonal and early postnatal mice: a qualitative and quantitative study. Arch Histol Jpn. 1984 Aug;47(3):239–250. doi: 10.1679/aohc.47.239. [DOI] [PubMed] [Google Scholar]
- Sasaki K., Matsumura G., Ito T. Morphometric analysis of postnatal erythropoiesis in the spleen and bone marrow of the mouse. Arch Histol Jpn. 1982 Jul;45(3):247–255. doi: 10.1679/aohc.45.247. [DOI] [PubMed] [Google Scholar]
- Terzakis J. A. The nucleolar channel system of human endometrium. J Cell Biol. 1965 Nov;27(2):293–304. doi: 10.1083/jcb.27.2.293. [DOI] [PMC free article] [PubMed] [Google Scholar]