Table 3.
Problem behavior at 12 years after GH cessation or at around age 30 years
Study group | Comparison groups | |||||
---|---|---|---|---|---|---|
SGA-GH | SGA-S | SGA-CU | AGA | All adults born SGA | ||
mean (SD) | mean (SD) | mean (SD) | mean (SD) | P-value | mean (SD) | |
Depressed/anxious | 55.1 (7.2)a | 56.4 (8.9)b | 54.4 (6.6) | 52.8 (5.4) | .02 | 55.1 (7.4)d |
Withdrawn | 55.1 (6.1) | 54.9 (7.1) | 54.8 (6.4) | 54.1 (5.4) | .52 | 55.0 (6.4) |
Somatic complaints | 55.6 (7.7)a | 55.8 (8.3)b | 56.0 (7.0)c | 52.8 (4.1) | .01 | 55.8 (7.5)d |
Thought problems | 54.6 (6.3)a | 54.2 (6.9) | 53.0 (4.5) | 52.8 (4.5) | .15 | 53.9 (5.9) |
Attention problems | 55.5 (5.5)a | 54.6 (5.8) | 54.4 (4.5) | 53.6 (4.5) | .08 | 54.9 (5.3) |
Aggressive behavior | 52.8 (3.8) | 52.8 (3.7) | 52.7 (4.1) | 52.2 (3.6) | .28 | 52.8 (3.8) |
Rule-breaking behavior | 53.0 (3.7)a | 51.8 (2.1) | 52.3 (3.2) | 51.7 (2.6) | .20 | 52.5 (3.3) |
Intrusive | 52.1 (3.6) | 52.0 (3.3) | 51.6 (3.2) | 51.4 (3.3) | .22 | 51.9 (3.4) |
Total scores | ||||||
Internalizing problems | 51.9 (10.7)a | 53.2 (11.5)b | 51.2 (11.1)c | 47.5 (9.6) | .01 | 51.9 (11.0)d |
Externalizing problems | 48.0 (8.3)a | 48.1 (6.8) | 47.2 (8.2) | 44.9 (8.5) | .07 | 47.7 (7.9) |
Total problems | 48.7 (9.9)a | 49.5 (8.8)b | 48.1 (8.2) | 45.3 (8.8) | .047 | 48.6 (9.1)d |
The Adolescent Behavior Check List questionnaire was completed by subjects 12 years after GH cessation. Scores are presented as mean (SD). Lower scores indicate less problem behavior. Bold P-values are considered significant differences between groups.
Abbreviations: AGA, appropriate for gestational age with normal height; SGA, small for gestational age; SGA-CU, small for gestational age with spontaneous catch-up growth to normal height; SGA-S, small for gestational age with short stature.
a P < .05 between SGA-GH adults and AGA adults.
b P < .05 between SGA-S adults and AGA adults.
c P < .05 between SGA-CU adults and AGA adults.
d P < .05 between all adults born SGA and AGA adults.