Table 1. Demographic and clinical characteristics of discovery cohort patients (n=5).
Characteristics | Responder (n=3) | Non-responder (n=2) |
---|---|---|
Age, median [range] | 74 [70–75] | 74 [73–75] |
Gender, n (%) | ||
Female | 1 (33.33) | 1 (50.00) |
Male | 2 (66.67) | 1 (50.00) |
PD-L1 (CPS), n (%) | ||
>10 | 1 (33.33) | 1 (50.00) |
1–10 | 2 (66.67) | 0 |
<1 | 0 | 1 (50.00) |
Tumor location, n (%) | ||
Esophagogastric junction & Fundus of stomach | 1 (33.33) | 1 (50.00) |
Body of stomach | 1 (33.33) | 0 |
Antrum | 1 (33.33) | 0 |
Lesser curvature of stomach | 0 | 1 (50.00) |
MMR/MSI, n (%) | ||
MSS | 3 (100.00) | 2 (100.00) |
Histology, n (%) | ||
Signet-ring cell | 0 | 1 (50.00) |
Poorly differentiated adenocarcinoma | 2 (66.67) | 0 |
Moderately differentiated adenocarcinoma | 1 (33.33) | 1 (50.00) |
PD-L1, programmed death-ligand 1; CPS, combined positive score; MMR, mismatch repair; MSI, microsatellite instability; MSS, microsatellite stability.