Table 7. Comparison of state-of-the-art methods in AD and NC classification.
| Study | Modality | Participants (AD/NC) | ACC (%) | SEN (%) | SPE (%) | AUC (%) |
|---|---|---|---|---|---|---|
| Zhao et al. (39) | sMRI | 419/832 | 92.7 | 91.9 | 94.6 | 97.2 |
| Zhang et al. (40) | sMRI | 353/650 | 91.3 | 91.0 | 91.9 | 98.4 |
| Wang et al. (41) | fMRI | 118/185 | 90.4 | 95.9 | 83.2 | 89.1 |
| Kong et al. (42) | sMRI + PET | 111/130 | 93.2 | 91.4 | 95.4 | – |
| Zhang et al. (43) | sMRI + PET | 129/110 | 91.1 | 91.0 | 91.0 | 94.1 |
| Tian et al. (44) | sMRI + DTI + fMRI | 191/167 | 88.7 | 86.8 | 90.9 | 88.8 |
| Proposed MSRNet | sMRI | 282/603 | 92.8 | 88.2 | 95.0 | 95.6 |
–, the cited paper does not provide data. AD, Alzheimer’s disease; NC, normal control; ACC, accuracy; SEN, sensitivity; SPE, specificity; AUC, area under the curve; sMRI, structural magnetic resonance imaging; PET, positron emission tomography; DTI, diffusion tensor imaging; fMRI, functional magnetic resonance imaging.