Table 3. Clinical data among the groups with different severity of CHD.
| Variable | Group 1 (normal) | Group 2 (mild CHD) | Group 3 (moderate CHD) | Group 4 (severe CHD) | P value |
|---|---|---|---|---|---|
| Number of subjects | 412 | 288 | 200 | 100 | – |
| Age (years) | 51.2±8.4 | 56.8±9.6 | 61.4±10.2 | 66.3±11.1 | <0.001 |
| Sex (male/female) | 192/220 | 160/128 | 112/88 | 48/52 | <0.001 |
| BMI (kg/m2) | 23.4±2.8 | 24.2±3.1 | 25.6±3.4 | 26.8±3.7 | <0.001 |
| Systolic blood pressure (mmHg) | 128.6±14.2 | 132.8±15.4 | 136.4±16.3 | 140.2±17.1 | <0.001 |
| Diastolic blood pressure (mmHg) | 80.4±9.8 | 82.6±10.2 | 84.2±10.6 | 86.4±11.1 | <0.001 |
| Fasting blood glucose (mmol/L) | 5.2±1.1 | 5.4±1.2 | 5.6±1.3 | 5.8±1.4 | <0.001 |
| Total cholesterol (mmol/L) | 4.6±1.0 | 4.8±1.1 | 5.0±1.2 | 5.2±1.3 | <0.001 |
| Triglyceride (mmol/L) | 1.4±0.7 | 1.6±0.8 | 1.8±0.9 | 2.0±1.0 | <0.001 |
| High-density lipoprotein (mmol/L) | 1.4±0.3 | 1.3±0.3 | 1.2±0.3 | 1.1±0.3 | <0.001 |
| Low-density lipoprotein (mmol/L) | 2.7±0.8 | 2.9±0.9 | 3.1±1.0 | 3.3±1.1 | <0.001 |
| Smoking (yes/no) | 112/300 | 120/168 | 56/144 | 24/76 | <0.001 |
| Family history of CHD (yes/no) | 64/348 | 56/232 | 28/172 | 16/84 | <0.001 |
Data are presented as mean ± standard deviation or number. CHD, coronary heart disease; BMI, body mass index.