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. 2024 Oct 18;14(12):8347–8360. doi: 10.21037/qims-24-753

Table 2. Arithmetic mean of the global and quadrantal peripapillary intraretinal layer thickness and results of statistical difference (µm).

Layer ASD NT P
RNFL 130.53±16.36 127.11±13.43 0.106a
GCL* 14.15±1.30 13.71±1.67 0.022a
   ST 11.86±2.23 11.68±2.01 0.700c
   SN 12.89±2.83 12.73±2.62 0.774c
   N 14.79±2.23 14.83±2.84 0.283a
   IN* 12.48±1.76 11.86±2.11 0.035a
   IT* 11.58±2.41 10.55±1.62 0.030a
   T* 17.41±1.97 16.69±2.44 0.018a
IPL 29.23±1.51 28.96±1.22 0.360c
INL* 16.69±1.88 15.59±1.88 <0.001a,**
   ST 15.10±2.79 14.35±1.74 0.128b
   SN 14.59±2.44 14.13±3.01 0.159a
   N* 16.63±2.60 15.72±2.86 0.037a
   IN* 15.06±2.88 13.84±2.40 0.006a
   IT* 14.85±2.69 13.44±2.02 0.006c
   T* 20.33±3.00 18.86±2.88 0.019c
OPL 25.26±1.21 24.95±1.18 0.215c
HOAM 59.06±4.75 60.26±7.45 0.344a
EZ 14.38±1.60 13.94±1.42 0.162c
OS 9.42±1.50 9.53±1.47 0.716c
OPRS 11.81±3.48 11.74±2.27 0.917b
RPE 20.53±0.94 20.52±0.55 0.211a

Data are presented as mean ± standard deviation. a, Mann-Whitney U test; b, Welch’s t-test; c, Student’s t-test. *, significant differences; **, significant results after Bonferroni correction. ASD, autism spectrum disorder; NT, neurotypical; RNFL, retinal nerve fiber layer; GCL, ganglion cell layer; ST, supero-temporal quadrant; SN, supero-nasal quadrant; N, nasal quadrant; IN, infero-nasal quadrant; IT, infero-temporal quadrant; T, temporal quadrant; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform; HOAM, Henle fiber layer/outer nuclear layer/myoid zone; EZ, ellipsoid zone; OS, outer segment; OPRS, outer segment PR/RPE complex and subretinal virtual space; PR, photoreceptor; RPE, retinal pigment epithelium.