Table 1. MR features of FNHs in training and validation set.
| Variable | Training cohort | Validation cohort | |||||
|---|---|---|---|---|---|---|---|
| ≤3 cm (n=88) | >3 cm (n=166) | P value | ≤3 cm (n=43) | >3 cm (n=66) | P value | ||
| Size (cm) | 2.0±0.7 | 5.5±2.0 | <0.001 | 2.1±0.6 | 5.5±2.0 | <0.001 | |
| Hepatic steatosis | 25 (28.4) | 47 (28.3) | 0.987 | 15 (34.9) | 17 (25.8) | 0.307 | |
| Intralesional fat | 6 (6.8) | 7 (4.2) | 0.552 | 4 (9.3) | 1 (1.5) | 0.078 | |
| Morphology | <0.001 | <0.001 | |||||
| Round | 65 (73.9) | 40 (24.1) | 34 (79.1) | 16 (24.2) | |||
| Lobulated | 23 (26.1) | 126 (75.9) | 9 (20.9) | 50 (75.8) | |||
| DWI | 0.860 | 0.598 | |||||
| Isointense | 10 (11.4) | 16 (9.6) | 6 (14.0) | 7 (10.6) | |||
| Hyperintense | 78 (88.6) | 150 (90.4) | 37 (86.0) | 59 (89.4) | |||
| ADC (×10−3 mm2/s) | 1.6±0.4 | 1.7±0.4 | 0.661 | 1.7±0.4 | 1.7±0.5 | 0.702 | |
| T1WI | 0.028 | 0.031 | |||||
| Hypointense | 53 (60.2) | 76 (45.8) | 28 (65.1) | 29 (43.9) | |||
| Isointense | 35 (39.8) | 90 (54.2) | 15 (34.9) | 37 (56.1) | |||
| T2WI | 0.031 | 0.002 | |||||
| Isointense | 30 (34.1) | 80 (48.2) | 9 (20.9) | 33 (50.0) | |||
| Hyperintense | 58 (65.9) | 86 (51.8) | 34 (79.1) | 33 (50.0) | |||
| Homogeneity on T2WI | <0.001 | 0.191 | |||||
| Homogenous | 82 (93.2) | 113 (68.1) | 37 (86.0) | 50 (75.8) | |||
| Heterogeneous | 6 (6.8) | 53 (31.9) | 6 (14.0) | 16 (24.2) | |||
| Enhancing capsule | 7 (8.0) | 66 (39.8) | <0.001 | 2 (4.7) | 27 (40.9) | 0.001 | |
| Central scar | 34 (38.6) | 140 (84.3) | <0.001 | 16 (37.2) | 56 (84.8) | <0.001 | |
| Feeding artery | 9 (10.2) | 93 (56.0) | <0.001 | 8 (18.6) | 29 (43.9) | 0.006 | |
| Radiating septa | 28 (31.8) | 128 (77.1) | <0.001 | 11 (25.6) | 50 (75.8) | <0.001 | |
| Enhancement pattern | 0.004 | 0.003 | |||||
| Hyper/hyper/hyper | 41 (46.6) | 47 (28.3) | 26 (60.5) | 20 (30.3) | |||
| Hyper/hyper-iso/iso | 47 (53.4) | 113 (68.1) | 17 (39.5) | 45 (68.2) | |||
| Hyper/hypo/hypo | 0 (0) | 6 (3.6) | 0 (0) | 1 (1.5) | |||
Data are presented as mean ± standard deviation or number (%). MR, magnetic resonance; FNH, focal nodular hyperplasia; DWI, diffusion-weighted imaging; ADC, apparent diffusion coefficient; T1WI, T1-weighted imaging; T2WI, T2-weighted imaging; hyper, hyperintense; iso, isointense; hypo, hypointense.