Table 1.
Characteristics | Overall | Cystatin C and creatinine tested | Only creatinine tested |
---|---|---|---|
N | 552909 | 37100 | 515809 |
eGFRcr (SD), ml/min per 1.73m2 | 90 (22) | 75 (27) | 91 (21) |
eGFRcys (SD), ml/min per 1.73m2 | 69 (32) | 69 (32) | |
KDIGO G-stage by eGFRcr, % | |||
eGFR 90 + ml/min per 1.73m2 | 55 | 33 | 57 |
eGFR 60–89 ml/min per 1.73m2 | 36 | 38 | 36 |
eGFR 45–59 ml/min per 1.73m2 | 5.6 | 14 | 5.1 |
eGFR 30–44 ml/min per 1.73m2 | 2.3 | 9.5 | 1.8 |
eGFR <30 ml/min per 1.73m2 | 1.0 | 6.3 | 0.64 |
Any urine protein measured, % | 26 | 47 | 24 |
ACR/PCR measured, % | 13 | 34 | 11 |
Dipstick measured, % | 13 | 13 | 13 |
ACR/PCRa (IQI), mg/g | 14 (4–69) | 16.8 (4.4–110.6) | 8.0 (2.7–23.9) |
Dipstick + and above, % | 6.1 | 8.2 | 5.9 |
Age (SD), yr (OR per 10 yr) | 58 (19) | 63 (18) | 57 (19) |
Female, % | 55 | 46 | 55 |
Hypertension, % | 47 | 68 | 45 |
Hypertension medication use, % | 44 | 64 | 42 |
RAAS inhibitor use, % | 30 | 45 | 28 |
Diuretics, % | 19 | 34 | 18 |
Diabetes, % | 13 | 23 | 13 |
Statin, % | 19 | 29 | 18 |
History of coronary heart disease, % | 6.7 | 12 | 6.3 |
History of cerebrovascular disease, % | 5.7 | 9.8 | 5.4 |
History of heart failure, % | 5.5 | 13 | 5.0 |
History of peripheral artery disease, % | 1.2 | 2.7 | 1.04 |
History of atrial fibrillation, % | 8.0 | 15.8 | 7.4 |
Liver disease, % | 2.4 | 3.7 | 2.3 |
Recent cancer, % | 12 | 17 | 11 |
Chronic obstructive pulmonary disease, % | 4.1 | 6.8 | 3.9 |
Potassium >5 mmol/l, % | 0.28 | 1.1 | 0.22 |
Anemia by hemoglobin,b % | 4.3 | 9.1 | 4.0 |
Measurement from 2014 used as a representative cross-sectional sample. Percents are of the column sample.
ACR/PCR, albumin-to-creatinine ratio or protein-to-creatinine ratio ;eGFRcr, estimated glomerular filtration rate based on creatinine; eGFRcys, estimated glomerular filtration rate based on cystatin C; RAAS, renin-angiotensin-aldosterone system.
ACR measured in 2014, imputed by PCR if ACR was not available.
Anemia is defined as hemoglobin<12 g/dL for female and <13 g/dl for male.