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. 2024 Oct 10;9(12):3596–3599. doi: 10.1016/j.ekir.2024.10.003

Table 1.

Characteristics of individuals tested for creatinine and/or cystatin C in 2014

Characteristics Overall Cystatin C and creatinine tested Only creatinine tested
N 552909 37100 515809
eGFRcr (SD), ml/min per 1.73m2 90 (22) 75 (27) 91 (21)
eGFRcys (SD), ml/min per 1.73m2 69 (32) 69 (32)
KDIGO G-stage by eGFRcr, %
 eGFR 90 + ml/min per 1.73m2 55 33 57
 eGFR 60–89 ml/min per 1.73m2 36 38 36
 eGFR 45–59 ml/min per 1.73m2 5.6 14 5.1
 eGFR 30–44 ml/min per 1.73m2 2.3 9.5 1.8
 eGFR <30 ml/min per 1.73m2 1.0 6.3 0.64
Any urine protein measured, % 26 47 24
 ACR/PCR measured, % 13 34 11
 Dipstick measured, % 13 13 13
ACR/PCRa (IQI), mg/g 14 (4–69) 16.8 (4.4–110.6) 8.0 (2.7–23.9)
Dipstick + and above, % 6.1 8.2 5.9
Age (SD), yr (OR per 10 yr) 58 (19) 63 (18) 57 (19)
Female, % 55 46 55
Hypertension, % 47 68 45
Hypertension medication use, % 44 64 42
RAAS inhibitor use, % 30 45 28
Diuretics, % 19 34 18
Diabetes, % 13 23 13
Statin, % 19 29 18
History of coronary heart disease, % 6.7 12 6.3
History of cerebrovascular disease, % 5.7 9.8 5.4
History of heart failure, % 5.5 13 5.0
History of peripheral artery disease, % 1.2 2.7 1.04
History of atrial fibrillation, % 8.0 15.8 7.4
Liver disease, % 2.4 3.7 2.3
Recent cancer, % 12 17 11
Chronic obstructive pulmonary disease, % 4.1 6.8 3.9
Potassium >5 mmol/l, % 0.28 1.1 0.22
Anemia by hemoglobin,b % 4.3 9.1 4.0

Measurement from 2014 used as a representative cross-sectional sample. Percents are of the column sample.

ACR/PCR, albumin-to-creatinine ratio or protein-to-creatinine ratio ;eGFRcr, estimated glomerular filtration rate based on creatinine; eGFRcys, estimated glomerular filtration rate based on cystatin C; RAAS, renin-angiotensin-aldosterone system.

a

ACR measured in 2014, imputed by PCR if ACR was not available.

b

Anemia is defined as hemoglobin<12 g/dL for female and <13 g/dl for male.