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. 2024 Oct 10;9(12):3600–3603. doi: 10.1016/j.ekir.2024.09.024

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© 2024 International Society of Nephrology. Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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MGN therapeutic response to dupilumab. (a) and (c) Data shown are for total serum albumin levels, uPCR, and anti-PLA2R autoantibody titers (shown as inverse of the dilution) at the indicated time points for (a) Case 1 and (c) Case 2. Time span of the indicated therapies is shown above the graph. (b) Diagnosis of Case 2 using immunofluorescence with isotype-specific antibodies on kidney biopsies. CP, cyclophosphamide; LD CsA, low-dose cyclosporin/tacrolimus; MGN, membranous glomerulonephritis; MMF, mycophenolate; MPR, modified Ponticelli regimen, uPCR, urine protein-to-creatinine ratios.