Table 2.
Baseline characteristics of 1943 Black Adults in the PURE cohort
| Characteristics | N = 1943 |
|---|---|
| Male, n (%) | 723 (37.2) |
| Age, yrs | 49.7 ± 10.4 |
| HIV positive, n (%) | 307 (15.9) |
| Anthropometric measurements | |
| BMI (kg/m2) | 24.7 ± 7.0 |
| Waist circumference (cm) | 79.8 ± 13.0 |
| Waist to Height ratio | 0.50 ± 0.09 |
| Cardiovascular profile | |
| Clinic SBP (mm Hg) | 133.0 ± 24.1 |
| Clinic DBP (mm Hg) | 87.7 ± 14.5 |
| Hypertension, n (%) | 1017 (52.3) |
| Clinic BP ≥ 140 and/90 mm Hg and no BP medication | 695 (35.8) |
| Clinic BP ≥ 140 and/90 mm Hg and using BP medication | 223 (11.5) |
| Clinic BP < 140/90 mm Hg and using BP medication | 99 (5.0) |
| Kidney function | |
| eGFR (ml/min per 1.73 m2) (n = 1574) | 98.3 ± 18.9 |
| GFR <60 ml/min per 1.73 m2 | 58 (3.68) |
| UACR (mg/mmol) | 0.71 (0.14–7.95) |
| Urinary creatinine (mg/dl) | 86.7 (23.6–246.0) |
| Urinaryspot Na+ (mmol/l) | 114.0 ± 57.1 |
| Urinaryspot K+ (mmol/l) | 30.3 (7.2–86.8) |
| Urinaryspot Na+/K+ ratio (mmol/l) | 3.2 (0.9–9.5) |
| Uric acidspot (mg/dl) | 21.4 (7.1–62.1) |
| Osmolality (mOsm/kgH2O) | 529 ± 222 |
| Uromodulin (μg/ml) | 34.0 (7.4–154.0) |
| Male | 35.1 (7.3–154.7) |
| Female | 33.4 (7.5–153.5) |
| Uromodulin (mg/g creatinine) | 39.3 (10.8–99.0) |
| Male | 36.4 (9.8–98.3) |
| Female | 41.1 (11.3–99.8) |
| Renin-Angiotensin-Aldosterone Profile | |
| Plasma Renin (pg/ml) | 4.6 (1.2–23.9) |
BMI, body mass index; CKD-EPI eGFR, Chronic Kidney Disease Epidemiology Collaboration no race formula estimated glomerular filtration rate; DBP, diastolic blood pressure; K+, potassium; Na+, sodium; SBP, systolic blood pressure; UACR, urine albumin-to-creatinine ratio.
Mean ± SD; geometric mean (5th and 95th percentiles).