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. 2024 Dec 4;15:1381060. doi: 10.3389/fendo.2024.1381060

Table 2.

Clinical characteristics of study population grouped by RBP4 interquartile range.

Study population (2117)
Characteristic RBP4(Q1) RBP4(Q2) RBP4(Q3) RBP4(Q4) P
Age (years) 50.92 (14.25) 55.85 (13.39) 58.12 (12.34) 59.32 (11.67) <0.001
Prevalence of hypertension (%) 166 (31.3%) 269 (50.9%) 281 (53.1%) 338 (63.9%) <0.001
Prevalence of diabetes (%) 33 (6.2%) 55 (10.4%) 70 (13.2%) 81 (15.3%) <0.001
Prevalence of insulin resistance (%) 105 (19.8%) 155 (29.3%) 191 (36.1%) 276 (52.2%) <0.001
Prevalence of metabolic syndrome (%) 62 (11.7%) 124 (23.4%) 203 (38.4%) 356 (67.3%) <0.001
Prevalence of hyperuricemia (%) 52 (9.8%) 138 (26.1%) 192 (36.3%) 267 (50.5%) <0.001
Prevalence of chronic kidney diseases(%) 50 (9.4%) 85 (16.1%) 90 (17.0%) 185 (35.0%) <0.001
physical examination
SBP (mmHg) 126 (19) 135 (20) 136 (19) 141 (18) <0.05
DBP (mmHg) 78 (10) 83 (10) 83 (10) 86 (11) <0.05
BMI (kg/m2) 22.87 (3.27) 23.93 (3.35) 24.72 (3.49) 25.37 (3.23) <0.001
WC (cm) 79.42 (9.66) 83.85 (9.29) 86.88 (9.46) 88.79 (8.74) <0.001
laboratory examination
FPG (mmol/L) 5.00 (1.00) 5.21 (1.17) 5.39 (1.25) 5.60 (1.62) <0.001
TG (mmol/L) 1.00 (0.34) 1.25 (0.42) 1.51 (0.58) 2.64 (1.44) <0.001
HDL-C(mmol/L) 1.59 (0.33) 1.54 (0.32) 1.52 (0.35) 1.35 (0.33) <0.001
HOMA-IR (mmol/L.mU/L) 1.65 (1.21-1.65) 1.95 (1.44-2.88) 2.18 (1.48-3.32) 2.78 (1.90-3.93) <0.001
Serum creatinine (µmol/mL) 69.58 (13.40) 74.79 (16.35) 80.25 (19.20) 86.77 (36.15) <0.001
Blood Urea Nitrogen (mmol/L) 4.77 (1.27) 5.16 (1.21) 5.48 (1.37) 5.69 (2.07) <0.001
eGFR (mL/min/1.73 m2) 93.89 (15.59) 87.53 (16.40) 82.39 (15.41) 78.33 (18.10) <0.001
Serum uric acid (µmol/L) 299.27 (71.07) 338.97 (76.95) 364.67 (84.04) 395.97 (90.72) <0.001
hs-CRP (mg/L) 1.00 (0-1.92) 1.27 (0.54-2.44) 1.51 (0.70-2.75) 1.70 (0.91-2.86) <0.001