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. 2024 Dec 4;11:1489671. doi: 10.3389/fmed.2024.1489671

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Copyright © 2024 Wang, Wang, Zhou, Shi, Hua and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evolution of liver function and blood routine test in response to pegylated interferon-α-2b over 48 weeks in all enrolled patients with hepatitis B virus-related compensated liver cirrhosis. Changes of (A) alanine aminotransferase (ALT) level, (B) aspartate aminotransferase (AST) level, (C) albumin level, (D) white blood cells (WBC) count, (E) neutrophils count, (F) platelets count, (G) hemoglobin (HGB) level at different observational time points. The points indicate median or mean, while the bars indicate interquartile range or standard deviation. Statistical analyses were performed using Kriskal-Wallis H test followed by Dunn’s multiple comparison test or one-way analysis of variance followed by Tukey test. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 compared with baseline.