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PK/PDCO values for PTA of 90% of a LA product at dosage of 20 mg/kg administered i.m. and dose intervals of 24, 48 and 72 h.
| Dose | Dose interval | PD target (fAUC/MIC)* | PK/PDCO calf (mg/L) | PK/PDCO adult cattle (mg/L) |
|---|---|---|---|---|
| 20 mg/kg i.m. | 24 h | 24 h | 2.18 | 3.74 |
| 20 mg/kg i.m. | 48 h | 24 h | 1.09 | 1.87 |
| 20 mg/kg i.m. | 72 h | 24 h | 0.73 | 1.25 |
*The fAUC used is the fAUC0-1,000h, divided by the dose interval.
