Figure 3.

Decrease of striatal PV⁺ cells in VPA-exposed animals. Representative microphotographs of the NSt from control (A) and VPA (B) animals showing the distribution of PV⁺ cells. Formal quantification of immune-positive cells was performed in the dorsomedial (A2, B2) and dorsolateral (A3, B3) regions of the striatum, indicated by squares in A1 and B1. The reduction in the PV labeling of cells was greater in the DLSt (see A2 vs B2) than in the DMSt (see A3 vs B3). C, Summary plots of seven brains from each group of animals (control, black; VPA, blue). *p < 0.05; **p < 0.01; ***p < 0.001.