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. 2024 Dec 3;15:1506398. doi: 10.3389/fphar.2024.1506398

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Copyright © 2024 Wang, Long, Peng, Li, Zhou, Wang and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DPDS intervention extenuated oxidative stress damage in kidney of the DKD rats (means ± SEM). (A) SOD activities in kidney (n = 10). (B) GSH levels in kidney (n = 10). (C) T-AOC activities in kidney (n = 10). (D) MDA levels in kidney (n = 10). (E) Representative images of Western blot (n = 4). (F) The relative density analysis of Nrf2 (n = 4). (G) The relative density analysis of NQO-1 (n = 4). (H) The relative density analysis of HO-1 (n = 4). (I) The relative density analysis of Keap1 (n = 4). ^# p < 0.05; ^## p < 0.01 vs. Mod group; *p < 0.05; **p < 0.01 vs. Mod group.