Table 5.

Effects of RC on T2D, mediated through IR

Causal mediation analysis	OR (95% CI)	Proportion (%)
Model 1
Indirect effect	1.07 [1.06, 1.07]	54.3%
Direct effect	1.06 [1.04, 1.06]	45.7%
Total effect	1.13 [1.11, 1.14]	100%
Model 2
Indirect effect	1.06 [1.05, 1.06]	54.1%
Direct effect	1.05 [1.04, 1.06]	45.9%
Total effect	1.11 [1.10, 1.12]	100%

Mediation analysis results were presented to illustrate the effects of RC on T2D, mediated through IR. The OR and 95% CI were shown for the indirect effect (mediated by IR), direct effect, and total effect of RC on T2D. Model 1 was unadjusted; Model 2 was adjusted for age, gender, and ethnicity. Abbreviations: RC, remnant cholesterol; T2D, type 2 diabetes; IR, insulin resistance; OR, odds ratio; CI, confidence interval