TABLE 1.

Alignment of major ospC groups with ospC alleles identified by SSCP analysis

Major ospC group	ospC allele	GenBank accession no.a	No. of the indicated ospC group in isolates fromb:
			Ticks	Human skin	Secondary sites of human infection
A	1	AF029860	17	23	21
B	2	AF029861	17	19	4
C	3	AF029862	11	3	0
D	4	AF029863	10	1	0
E	5, 7	AF029864	6	1	0
F	6	AF029865	9	0	0
G	8	AF029867	5	7	0
H	9	AF029868	7	6	0
I	10	AF029869	1	9	3
J	11, 18	AF029870	3	7	0
K	12, 13	AF029871	6	32	16
L		L42899	2	0	0
M	14	U01892	1	3	0
N	15	L42899	1	3	0
O		X84778	0	1	0
Pc		U91796	1	0	0
Qc		U91790	1	0	0
Rc		U91791	2	0	0
Sc		U91793	1	0	0
T	16	AF065143	0	1	0
U	17	AF065144	0	2	0

^aA single GenBank sequence for each type is given as an example. The complete list of sequences is given in reference 40. 

^bThe number of each major ospC group observed. This includes both SSCP data and data from the literature, including GenBank. 

^cB. burgdorferi sensu stricto groups P through S are found only in Europe. Groups R and S are excluded from the analysis because nearly identical ospC alleles are found in B. afzelii and B. garinii, showing that these groups were recently created by cross-species transfer.