FIG. 2.

Structure of the mBD-3 gene. (A) Schematic drawing of the gene, the cDNA, and the predicted structure of the prepropeptide. The gene is represented schematically, with the following components shown: 5′ untranslated region (5′ UTR), signal sequence, interrupted prosequence (PRO), mature peptide (MATURE), and 3′ UTR. (B) Nucleotide sequence of the mBD-3 promoter, with locations of the TATA box, an NF-κB binding site, the putative start of transcription (+1), and the start of the open reading frame (ORF) indicated.