Table 1.
Patients clinical features at ICU admission
|
Total n = 118 |
CMV DNAemia | P | ||
|---|---|---|---|---|
|
Yes (n = 21, 17.8%) |
No (n = 97, 82.2%) |
|||
| Age (yrs) | 67 (58–75) | 64 (58–74) | 68 (59–75) | 0.394 |
| Sex, n (%) | - | - | - | > 0.999 |
| Male | 94 (79.7) | 17 (81.0) | 77 (79.4) | - |
| Female | 24 (20.3) | 4 (19.0) | 20 (20.6) | - |
| Weight (kg) | 59.1 ± 14.0 | 56.2 ± 13.8 | 59.8 ± 14.0 | 0.295 |
| BMI (kg/m2) | 21.4 ± 4.5 | 20.8 ± 4.5 | 21.6 ± 4.4 | 0.482 |
| Score of disease severity | ||||
| APACHE II | 23 (18–29) | 23 (20–29) | 23 (18–28) | 0.921 |
| SOFA | 9 (7–12) | 8 (6–13) | 9 (7–12) | 0.924 |
| Causes of sepsis, n (%) | - | - | - | > 0.999 |
| sCAP | 114 (96.6) | 21 (100.0) | 93 (95.9) | - |
| Other | 4 (3.4) | 0 (0.0) | 4 (4.1) | - |
| Vital signs | ||||
| Average blood pressure (mmHg) | 85 ± 20 | 80 ± 18 | 86 ± 20 | 0.214 |
| Heart rate (bpm) | 100 (81–117) | 110 (85–120) | 98 (81–112) | 0.198 |
| Respiratory rate (bpm) | 20 (18–25) | 22 (20–26) | 20 (18–23) | 0.047# |
| Temperature (℃) | 36.8 (36.5–37.5) | 37.0 (36.5–37.8) | 36.8 (36.5–37.5) | 0.136 |
| Comorbidities, n (%) | ||||
| Hypertension | 58 (49.2) | 6 (28.6) | 52 (53.6) | 0.037# |
| Diabetes | 51 (43.2) | 10 (47.6) | 41 (42.3) | 0.654 |
| Cardiovascular diseases | 33 (28.0) | 7 (33.3) | 26 (26.8) | 0.546 |
| COPD | 33 (28.0) | 3 (14.3) | 30 (30.9) | 0.123 |
| CVA | 23 (19.5) | 5 (23.8) | 18 (18.6) | 0.805 |
| CKD | 17 (14.4) | 5 (23.8) | 12 (12.4) | 0.312 |
| ILD | 12 (10.2) | 3 (14.3) | 9 (9.3) | 0.772 |
ICU Intensive Care Unit, CMV Cytomegalovirus, DNAemia DNA detection by quantitative polymerase chain reaction (qPCR) on peripheral blood samples, BMI Body Mass Index, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sequential Organ Failure Assessment, sCAP Severe Community-acquired Pneumonia, COPD Chronic Obstructive Pulmonary Disease, CVA Cerebrovascular Accident, CKD Chronic Kidney Disease, ILD Interstitial Lung Disease
#P < 0.05; Categorical variables were expressed as n (%), Continuous variables were expressed as Mean ± SD or Median (IQRs); Bold font indicates the difference was statistically significant