Table 2.

Antiprotozoal activities of selected extract, fractions, compound (1), and standard drugs

Extract/fractions code	Yield (%)	Activity against protozoa (IC50 µg/mL)
		P. falciparum	E. histolytica	L. donovani	T. brucei rhodesiense
Ca.RD	0.357	0.1	8.2	0.6	0.9
Ca.RD-D1	0.007	inactive	inactive	inactive	Inactive
Ca.RD-D2	0.003	inactive	inactive	inactive	10.3
Ca.RD-D3	0.004	6.2	inactive	9.5	1.7
Ca.RD-D4	0.008	6.6	inactive	inactive	3.5
Ca.RD-D5	0.009	6.0	inactive	9.6	1.3
Ca.RD-D6	0.008	0.8	4.4	0.4	0.1
Ca.RD-D7	0.009	5.8	1.6	0.2	0.1
Ca.RD-D8	0.003	1.7	1.6	1.2	0.6
Ca.RD-D9	0.010	3.3	inactive	inactive	inactive
Ca.RD-D10	0.242	1.9	6.8	0.7	inactive
Compound (1)	0.005	2.3	0.3	0.1	0.1
Metronidazole		-	2.6	-	-
Amphotericin B		-	-	0.3	-
Pentamidine		-	-	-	0.06
Chloroquine		1.8	-	-	-

Data was presented as a mean of triplicate; inactive data means the IC₅₀ is more than 10 µg/mL