Table 4.
CKD progression | Overall (%; 95% CI) | Stage 3a (eGFR 45–59) (%; 95% CI) | Stage 3b (eGFR 30–44) (%; 95% CI) | Stage 4 (eGFR 15–39) (%; 95% CI) | Stage 5 (eGFR <15) (%; 95% CI) |
---|---|---|---|---|---|
Overall | |||||
No change | 48 895 (55.4%; 55.1% to 55.7%) | 26 613 (68.6%; 68.2% to 69.1%) | 10 590 (41.6%; 41.0% to 42.2%) | 4811 (34.2%; 33.4% to 35.0%) | 6881 (68.9%; 68.0% to 69.8%) |
Improved* | 16 237 (18.4%; 18.1% to 18.7%) | 1227 (3.2%; 3.0% to 3.3%) | 7344 (28.6%; 28.3% to 29.4%) | 4561 (32.5%; 31.7% to 33.2%) | 3105 (31.1%; 30.2% to 32.0%) |
Progressed† | 23 141 (26.2%; 25.9% to 26.5%) | 10 930 (28.2%; 27.7% to 28.6%) | 7528 (29.6%; 29.0% to 30.1%) | 4683 (33.3%; 32.5% to 34.1%) | – |
People living with diabetes | |||||
No change | 5720 (50.6%; 49.7% to 51.5%) | 2466 (56.9%; 55.4% to 58.4%) | 1627 (43.6%; 42.0% to 45.2%) | 930 (41.0%; 39.0% to 43.0%) | 697 (71.6%; 68.7% to 74.4%) |
Improved* | 1431 (12.7%; 12.1% to 13.3%) | 59 (1.4%; 1.0% to 1.7%) | 612 (16.4%; 15.2% to 17.6%) | 484 (21.3%; 19.7% to 23.1%) | 276 (28.4%; 25.6% to 31.3%) |
Progressed† | 4152 (36.7%; 35.8% to 37.6%) | 1807 (41.7%; 40.2% to 43.2%) | 1490 (40.0%; 38.4% to 41.5%) | 855 (37.7%; 35.7% to 39.7%) | – |
People living without diabetes | |||||
No change | 5866 (58.5%; 57.5% to 59.4%) | 2250 (66.6%; 65.0% to 68.2%) | 1218 (46.5%; 44.6% to 48.4%) | 648 (35.7%; 33.5% to 37.9%) | 1750 (78.8%; 77.1% to 80.4%) |
Improved* | 1646 (16.4%; 15.7% to 17.1%) | 77 (2.3%; 1.8% to 2.8%) | 630 (24.0%; 12.5% to 15.1%) | 467 (25.7%; 23.8% to 27.8%) | 472 (21.2%; 19.6% to 23.0%) |
Progressed† | 2523 (25.1%; 24.3% to 26.0%) | 1051 (31.1%; 29.6% to 32.7%) | 773 (29.5%; 27.8% to 31.3%) | 699 (38.5%; 36.3% to 40.8%) | – |
A patients CKD status was classified as ‘improved’ if they experienced an improvement in CKD stage and their eGFR function improved by at least 25% from baseline.
A patient’s CKD status was classified as ‘progressed’ if they experienced a drop in CKD stage and their eGFR function decreased by at least 25% from baseline.
CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate.