Table 5.
Crude and adjusted HRs estimating risk of CKD progression versus no change or improvement
| Risk factor | N (%) progressed | Total person time (years) | Rate per 100py (95% CI) | Crude HR (95% CI) | Adjusted HR (95% CI)* |
|---|---|---|---|---|---|
| Sex | |||||
| Male | 9019 (32.1%) | 67 725.1 | 13.3 (13.0 to 13.6) | ref. | ref. |
| Female | 14 122 (28.2.0%) | 127 145.1 | 11.1 (10.9 to 11.3) | 0.88 (0.85 to 0.90) | 0.92 (0.87 to 0.97) |
| Age (years) | |||||
| 18–29.9 | 721 (27.8%) | 6033.8 | 11.9 (11.1 to 12.9) | ref. | ref. |
| 30–39.9 | 1771 (24.8%) | 18 036.7 | 9.8 (9.4 to 10.3) | 0.91 (0.83 to 0.99) | 1.08 (0.87 to 1.35) |
| 40–49.9 | 2998 (26.1%) | 30 224.5 | 9.9 (9.6 to 10.3) | 0.98 (0.90 to 1.06) | 1.24 (1.01 to 1.51) |
| 50–59.9 | 4873 (23.1%) | 42 897.6 | 11.4 (11.0 to 11.7) | 1.17 (1.08 to 1.26) | 1.36 (1.13 to 1.65) |
| 60+ | 12 778 (31.4%) | 97 704.6 | 13.1 (12.9 to 13.3) | 1.44 (1.34 to 1.56) | 1.40 (1.16 to 1.69) |
| Diabetes* | |||||
| No | 2523 (32.3%) | 18 480.3 | 13.7 (13.1 to 14.2) | ref. | ref. |
| Yes | 4152 (40.2%) | 24 291.2 | 17.1 (16.6 to 17.6) | 1.48 (1.41 to 1.57) | 1.43 (1.36 to 1.51) |
| HIV/TB status | |||||
| HIV−/TB− | 17 897 (29.7%) | 150 874.6 | 11.9 (11.7 to 12.0) | ref. | ref. |
| HIV+/TB− | 3761 (29.2%) | 31 006.5 | 12.1 (11.7 to 12.5) | 1.03 (1.00 to 1.07) | 1.04 (0.97 to 1.11) |
| HIV−/TB+ | 1179 (29.0%) | 10 297.0 | 11.4 (10.8 to 12.1) | 0.97 (0.91 to 1.03) | 0.97 (0.87 to 1.09) |
| HIV+/TB+ | 304 (27.5%) | 2719.2 | 11.2 (10.0 to 12.5) | 0.99 (0.88 to 1.11) | 0.97 (0.78 to 1.19) |
*
Among those with a diabetes lab (n=22 025).
CKD, chronic kidney disease; PY, person-years.