Figure 5.

The absence of the thymic stromal lymphopoietin (TSLP)/TSLP receptor (TSLPR) signaling pathway impairs T regulatory (Treg) cells infiltration in cardiac tissue post-MI. (A) The gating strategies employed in identifying infiltrated CD45⁺FVD^-CD4⁺T cells, CD45⁺FVD^-CD4⁺Foxp3⁺ Treg cells, and CD45⁺FVD^-CD4⁺Foxp3^- conventional T (Tconv) cells in the heart. (B–E) Absolute cell counts per gram of cardiac tissue and the Treg/Tconv cell ratio were determined on day 3 and day 7 post-MI (n = 5–9 per group). Data are presented as the mean ± SEM and were analyzed using unpaired t-test in (B–E).