FIGURE 8.

Genomic alterations of BIRC5 in lung cancer and their correlation with prognosis across clinical subgroups. (A) OncoPrint of BIRC5 alterations in cancer cohorts; (B) Detailed breakdown of BIRC5 gene alterations in lung cancer; (C) Major types of BIRC5 alterations; (D) Forest plot summarizing BIRC5’s prognostic value in different clinical subgroups; (E–J) Kaplan-Meier (KM) curves showing BIRC5 expression, prognosis, and disease progression in lung cancer, stratified by clinical factors (age, residual tumor status, etc.); (K) Time-dependent ROC curve predicting 1, 3, and 5-year survival; (L,M) LASSO model results with cross-validation for tuning parameter selection and coefficient profiles; (N) Risk score, survival status, and heatmap of eight genes in lung cancer patients.