Table 1.
Characteristics of the three patients at the diagnosis of DLBCL complicated with HBV-related cirrhosis.
| Variable | P1 | P2 | P3 |
|---|---|---|---|
| Sex | Male | Male | Female |
| Age (years) | 62 | 53 | 46 |
| DLBCL subtype | Non-GCB | Non-GCB | Non-GCB |
| Ann Arbor stage | IV B | II A | IV B |
| IPI score | 5 | 1 | 4 |
| Other high risks | – | Double expression | Double expression Relapsed disease |
| History of chronic HBV infection | Yes | Yes | Yes |
| HBV-DNA (range, <ra IU/mL) |
3.59×107 | <.5 | <.5 |
| HBV serology | HBsAg+ HBeAg+ HBcAb+ |
HBsAg+ HBeAb+ HBcAb+ |
HBsAg+ HBeAb+ HBcAb+ |
| Hepatic complications besides cirrhosis | Severe ascites; splenomegaly; esophageal varices | Splenomegaly | Esophageal and gastric varices |
| Child–Pugh grade | Grade B | Grade A | Grade A |
DLBCL, diffuse large B-cell lymphoma; HBV, hepatitis B virus; GCB, germinal center B-cell-like; IPI, International Prognostic Index.