Table 3.
Clinical access site‐related events according to manual compression versus any closure device in males and females.
| Clinical events | Manual | Any closure device | Odds ratio (95% CI) | p‐value |
|---|---|---|---|---|
| Manual versus any closure device | ||||
| Female | ||||
| Any 72‐h bleeding | 66/1482 (4.5%) | 44/2444 (1.7%) | 2.54 (1.73–3.74) | < 0.001 |
| Access site bleeding | 25/1482 (1.7%) | 18/2444 (0.7%) | 2.31 (1.26–4.25) | 0.007 |
| Hematoma | 32/1482 (2.2%) | 19/2444 (0.8%) | 2.82 (1.59–4.99) | < 0.001 |
| Retroperitoneal bleed | 11/1482 (0.7%) | 8/2444 (0.3%) | 2.28 (0.91–5.67) | 0.077 |
| Vascular complication | 12/1482 (0.8%) | 5/2444 (0.2%) | 3.98 (1.40–11.3) | 0.010 |
| Male | ||||
| Any 72‐h bleeding | 41/2613 (1.6%) | 39/4903 (0.8%) | 1.99 (1.28–3.09) | 0.002 |
| Access site bleeding | 9/2613 (0.3%) | 8/4903 (0.2%) | 2.11 (0.82–5.49) | 0.124 |
| Hematoma | 7/2613 (0.3%) | 10/4903 (0.2%) | 1.31 (0.50–3.46) | 0.580 |
| Retroperitoneal bleed | 1/2613 (0.04%) | 5/4903 (0.1%) | 0.38 (0.04–3.21) | 0.371 |
| Vascular complication | 8/2613 (0.3%) | 9/4903 (0.2%) | 1.67 (0.64–4.33) | 0.292 |