Table 5. Effect of the alkenyl substituent and counteranion in a cationic enantioselective Ir(i)-catalyzed PKR.
Entry | R | X | Solvent | Yield (%) | ee (%) |
---|---|---|---|---|---|
1 | H | TfO− | DME | 85 | 91 |
2 | " | BArF− | " | 69 | 85 |
3 | Me | TfO− | " | 9 | 58 |
4 | " | BArF− | " | Trace | — |
5 | " | TfO− | THF | 10 | 71 |
6 | " | BArF− | " | 28 | 64 |