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. 2024 Sep 12;16(4):1490–1505. doi: 10.1039/d4sc02645d

Table 6. Representative examples of a regio- and stereoselective Rh(i)-catalyzed [(2+2)+2] of 1,6-enynes containing various alkynyl and alkenyl substituent with an exogenous acrylamide.

graphic file with name d4sc02645d-u6.jpg
Entry x R1 R2 Yield (%) ee (%)
1 3 Me Me >99 >99
2 5 " Et 86 >99
3 10 H Ph 47 94