Table 7. Representative examples of the kinetic resolution of racemic secondary allylic alcohols in a Rh(i)-catalyzed [(2+2)+2] carbocyclization reaction.
Entry | Z | R | Yield (%) | ee (%) |
---|---|---|---|---|
1 | NTs | Ph | 68 | 99 |
2 | " | c-Hex | 79 | 99 |
3 | " | t-Bu | 20 | >99 |
4 | C(CO2Bn)2 | c-Hex | 42 | 99 |