Figure 1.

Clinical examination images

(A) Cumulative inflammatory scores of ocular examinations revealed only mild post-injection signs of mild inflammation for the first days after injection and in LD (□) horse 2 from days 28–49 and one HD horse 2 (Δ HD) at day 35 after dosing. (B) Mean intraocular pressures (IOPs) of the LD and HD eyes were significantly lower than the control saline-dosed eyes at variable time points from 28 to 84 days after injection. Data represented as mean ± SEM. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001; ANOVA with Tukey’s. (C) Representative clinical photographs of eyes at 63 days after injection.