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. 2024 Oct 28;32(4):101360. doi: 10.1016/j.omtm.2024.101360

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© 2024 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Representative histopathology

Saline-injected eyes had no inflammatory changes. LD eyes (LD1 and LD2) were injected with 3.75e−11 vgs and had slight, scattered lymphocytic/plasmocytic (LP) cells in the ciliary body, small foci of lymphocytes in the posterior iris (arrowheads), and normal retina in both eyes. In the HD eyes (HD1 and HD2), injected with 3.75e−12 vgs, there was diffuse moderate LP infiltration into the iris (arrowheads), ciliary body processes, and pars plana. Also, multifocal, diffuse inferior, moderate-sized nests of LP infiltrated the choroid (arrowheads), but the overlying retina appeared normal.