TABLE 1.
Characteristics of patients with OTSCC.
| Variables | Total (N = 518) | 5‐years (%) | p |
|---|---|---|---|
| Age (years) | 52 (43–61) | — | 0.014 |
| Sex | |||
| Male | 349 (67.4%) | 70.72 | 0.075 |
| Female | 169 (32.6%) | 78.4 | |
| BMI (kg/m2) | 22.5 (20.5–24.8) | — | 0.313 |
| Smoking | |||
| No | 338 (65.3%) | 75.7 | 0.025 |
| Yes | 180 (34.7%) | 68.78 | |
| Alcohol use | |||
| No | 426 (82.2%) | 74.06 | 0.158 |
| Yes | 92 (17.8%) | 69.89 | |
| Betel net | |||
| No | 484 (93.4%) | 75.03 | 0.004 |
| Yes | 34 (6.6%) | 37.91 | |
| Hypertension | |||
| No | 431 (83.2%) | 73.2 | 0.399 |
| Yes | 87 (16.8%) | 74.2 | |
| Diabetes | |||
| No | 471 (90.9%) | 74.66 | 0.008 |
| Yes | 47 (9.1%) | 59.34 | |
| Family history | |||
| No | 478 (92.3%) | 73.98 | 0.276 |
| Yes | 40 (7.7%) | 65.02 | |
| Differentiation | |||
| Well | 307 (59.3%) | 68.51 | 0.018 |
| Moderate‐poor | 211 (40.7%) | 79.51 | |
| Lymphovascular involvement | |||
| No | 495 (95.6%) | 74.35 | 0.006 |
| Yes | 23 (4.4%) | 50.72 | |
| Perineural invasion | |||
| No | 333 (64.3%) | 79.59 | < 0.001 |
| Yes | 185 (35.7%) | 60.49 | |
| Margin status | |||
| Negative | 513 (99%) | 73.92 | 0.106 |
| Positive | 5 (1%) | 40 | |
| pT stage | |||
| T1 | 156 (30.1%) | 89.41 | < 0.001 |
| T2 | 188 (36.3%) | 73.88 | |
| T3 | 164 (31.7%) | 57.08 | |
| T4 | 10 (1.9%) | 28.57 | |
| pN stage | |||
| N0 | 334 (64.5%) | 86.32 | < 0.001 |
| N1 | 57 (11%) | 59.86 | |
| N2 | 106 (20.5%) | 45.93 | |
| N3 | 21 (4.1%) | 42.49 | |
| ACRT | |||
| No | 422 (81.5%) | 75.5 | 0.011 |
| Yes | 96 (18.5%) | 63.02 | |
| Neck dissection | |||
| Laterality | 491 (94.8%) | 73.87 | 0.078 |
| Bilaterality | 27 (5.2%) | 64.96 | |
| No. of positive lymph nodes | 0 (0–1) | — | < 0.001 |
| No. of dissected lymph nodes | 20 (15–26) | — | 0.122 |
| Lower neck involvement | |||
| No | 499 (96.3%) | 74.86 | < 0.001 |
| Yes | 19 (3.7%) | 30.62 | |
| ENE | |||
| Negative | 495 (95.6%) | 74.53 | < 0.001 |
| Positive | 23 (4.4%) | 42.29 | |
| Laterality (N2c) | |||
| Unilaterality | 514 (99.2%) | 73.79 | 0.001 |
| Bilaterality | 4 (0.8%) | NA | |
Note: Continuous data are medians, with IQRs in parentheses.
Abbreviations: ACRT, adjuvant chemoradiotherapy; BMI, body mass index; ENE, extranodal extension; IQR, interquartile ranges; NA, not available; OTSCC, oral tongue squamous cell carcinoma.