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. 2024 Dec 18;16:181. doi: 10.1186/s13148-024-01792-x

Table 1.

Clinical and demographic features of 59 systemic lupus erythematosus participants by remission status at follow-up visit

Remission status
Yes No P-value
N 19 40
Female, n (%) 18 (94.74) 34 (85.00) 0.52
Self-reported race, n (%) 0.79
 White 1 (5.26) 6 (15.00)
 Black 3 (15.79) 6 (15.00)
 Asian 7 (36.84) 11 (27.50)
 Other 0 (0.00) 2 (5.00)
 Multiple racesa 1 (5.26) 2 (5.00)
Not reportedb 7 (36.84) 13 (32.50)
Hispanic, n (%) 7 (36.84) 15 (37.50) 1.00
Age at diagnosis (years), mean (sd) 35.68 (16.34) 27.05 (10.57) 0.02
Age at baseline flare visit (years), mean (sd) 40.68 (13.64) 35.88 (12.20) 0.18
Days between visits, median [IQR] 96.00 [57.00, 267.50] 78.50 [48.50, 163.25] 0.48
SELENA SLEDAI, mean (sd)
 Baseline 11.42 (5.65) 11.53 (5.85) 0.95
 Follow-up 0.00 (0.00) 5.72 (4.08)  < 0.001
SLEDAI Proteinuria, n (%)
 Baseline 8 (42.11) 17 (42.50) 1.00
 Follow-up 0 (0.00) 6 (15.00) 0.19
Medications at follow-up (yes/no), n (%)
 Prednisone 15 (78.95) 31 (77.50) 1.00
 Hydroxychloroquine 17 (89.47) 32 (80.00) 0.59
 Mycophenolate 7 (36.84) 15 (37.50) 1.00
 Azathioprine 0 (0.00) 7 (17.50) 0.13
 Belimumab 1 (5.26) 5 (12.50) 0.69
 Cyclophosphamide 1 (5.26) 3 (7.50) 1.00
 Solumedrol 1 (5.26) 0 (0.00) 0.70
 Rituximab 1 (5.26) 3 (7.50) 1.00
 Tacrolimus 0 (0.00) 2 (5.00) 0.82
 Methotrexate 3 (15.79) 5 (12.50) 1.00

Remission defined as SLEDAI = 0 at follow-up visit

IQR, interquartile range; sd, standard deviation; SLE, Systemic Lupus Erythematosus; SELENA SLEDAI, SLE Disease Activity Index—the Safety of Estrogens in Lupus Erythematosus: National Assessment trial

aAdditional race categories not solely indicated by participants included American Indian and Pacific Islander

bMajority of participants not reporting race identified as Hispanic