Table 3.

Validation of the CRIME-Q was performed based on a systematic review of 114 records on meningioma animal models [62] through agreement percentage and nominal Kappa index

SE standard error, QoR Quality of Reporting, MQ Methodological Quality, RoB Risk of Bias

^*Kappa index cannot be calculated due to too high agreement and/or too few rating items. The data reliability scores (interpretation) were based on McHugh(60) and Landis and Koch [61]. The full scoring from both reviewers is available in the published material of [18] online at: https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-023-04620-7#Sec29 (CRIME-Q full spread sheet)