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. 2024 Dec 18;20(1):2436241. doi: 10.1080/21645515.2024.2436241

Figure 7.

Figure 7.

Expression of tissue homing receptors on MV-specific human T cells. Human PBMCs were unstimulated (M) or stimulated in vitro for 20h with UV-inactivated measles Schwarz strain (MV) or UV-inactivated SARS-CoV-2 Wuhan strain (W) at an MOI of 1. The expression of ten different tissue homing markers was assessed by flow cytometry. Cells were gated on antigen-specific T cells (CD69+ activated T cells). CD62L and CD45RO expressions were used to identify naïve T cells (CD62L+ CD45RO−), central memory T cells (Tcm, CD62L+ CD45RO+), effector memory T cells (Tem, CD62L− CD45RO+) and terminally differentiated effector memory T cells (TEMRA, CD62L− CD45RO−). (a) Tissue homing receptors significantly over-expressed by measles-specific CD8+ T cells subpopulations. (b) Tissue homing receptors significantly over-expressed by measles-specific CD4+ T cells subpopulations. Each data point represents an individual human sample. Data are represented as median with IQR significant differences between the groups were determined by kruskal-wallis test, Dunn post-hoc test and a correction for multiple comparisons using the Benjamini–Hochberg correction (*p < .05 and fdr < 0.2).