Fig. 2.

Ecological landscape of the endothelial cell populations. A Single-cell atlas showing cell clusters of endothelial cells. B Marker genes specific to each subpopulation. C Single-cell atlas shows clusters of endothelial cells in control, DM and DFU groups. D Differences in abundance of various subpopulations of Endothelial cells in the control, DM and DFU groups. E Biological pathways involved in endothelial cells. F Trajectory and pseudo-time values of endothelial cells progression. The pie charts show the proportion of different groups in the cluster. G Gene regulatory network of the endothelial cell subpopulations. H Series of scatter plots demonstrating transcription factors regulating endothelial cell subpopulations