Table 1.
Clinical characteristics |
Group 1 (partial/complete regression, n=72) |
Group 2 (CIN2 progression and persistence, n=36) |
p-value |
Age, years (mean ± SD) |
31.72±4.31 |
32.40±4.79 |
0.86 |
Parity, n (%) |
Nulliparous: 31 (43.66%) |
Nulliparous: 16 (44.44%) |
0.82 |
Multiparous: 40 (56.33%) |
Multiparous: 20 (55.55%) |
||
Contraception, n (%) |
Yes: 23 (31.94%) |
Yes: 10 (27.77%) |
0.77 |
Smokers, n (%) |
Yes: 29 (40.27%) |
Yes: 19 (52.77%) |
0.19 |
Vaccination, n (%) |
Yes: 13 (18.05%) |
Yes: 8 (22.22%) |
0.68 |
Previous cytology, n (%) |
ASCUS: 16 (22.22%) |
ASCUS: 4 (11.11%) |
0.004 |
LSIL: 17 (23.61%) |
LSIL: 8 (22.22%) |
||
HSIL: 24 (33.33%) |
HSIL: 23 (63.88%) |
||
ASC-H: 15 (20.83%) |
ASC-H: 1 (2.77%) |
||
HPV genotyping, n (%) |
HPV16: 23 (31.94%) |
HPV16: 17 (47.22%) |
0.003 |
HPV18: 5 (6.94%) |
HPV18: 9 (25%) |
||
Other HR-HPV: 43 (61.11%) |
Other HR-HPV: 11 (30.55%) |
ASC-H: Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (HSIL); ASCUS: Atypical squamous cells of undetermined significance; CIN2: Cervical intraepithelial neoplasia 2; HPV: Human papillomavirus; HR: High risk; LSIL: Low-grade squamous intraepithelial lesion; n: No. of patients; SD: Standard deviation