Table 3.

Univariate and multivariable linear regression analyses for different predictors of the normalized minimum conduit area.

Variable	Univariate regression analysis		Multivariable regression analysis
	Slope (95% CI)	p value	Slope (95% CI)	p value
Female	3.67 (−20.67 to 28.01)	0.150	–
Mesocardia or dextrocardia	1.83 (−24.86 to 28.51)	0.892	–
Isomerism	−11.33 (−39.22 to 16.57)	0.422	–
Simple cardiac situs and position	5.29 (−17.58 to 28.16)	0.647
Dominant ventricle
Biventricle	Reference
Left ventricle	−19.14 (−49.07 to 10.80)	0.207	–
Right ventricle	−21.85 (−49.35 to 5.66)	0.118	–
Apicocaval juxtaposition	−13.77 (−36.71 to 9.18)	0.236	–
Bilateral bidirectional cavopulmonary connection	−18.78 (−43.18 to 5.62)	0.130	–
Use of antithrombotic drugs
No medication	Reference
Aspirin	−15.76 (−86.10 to 54.57)	0.657	–
Warfarin	3.55 (−70.96 to 78.06)	0.925	–
Age on Fontan procedure, year	5.18 (−2.55 to 12.91)	0.186	–
Weight at Fontan procedure, kg	−0.70 (−5.10 to 3.71)	0.754	–
Age on cardiac CT, year	−5.59 (−8.54 to −2.64)	<0.001
Normalized original conduit area, mm2/m2	0.22 (0.11–0.33)	<0.001	0.23 (0.13–0.32)	<0.001
Fenestration	−9.89 (−32.47 to 12.69)	0.386	–
Follow-up duration, year	−3.07 (−6.81 to 0.67)	0.067	–
Interval from Fontan procedure, year	−6.43 (−9.29 to −3.57)	<0.001	−6.65 (−9.20 to −4.10)	<0.001

CT = computed tomography.