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. 2024 Dec 19;19:169. doi: 10.1186/s13020-024-01041-6

Fig. 5.

Fig. 5

ZSWF prevented pericyte senescence in DCI mice. A Dotplot showing the expression levels of SASP genes (such as Ccl3, Tnfrsf10b, Nfkbid, Nfkb1, Plat, and Ang) in pericytes of each group. B Umap showing the expression levels of Cdna1a and SASP genes set (such as Ccl3, Tnfrsf10b, Nfkbid, Nfkb1, Plat, and Ang) in pericytes of each group. C Dotplot showing the communication intensity of Pdgfb-Pdgfrβ receptor and ligand pairs between endothelial cells and pericytes in each group. D Violin plot showing the distribution of expression levels of Pdgfb in endothelial cells of each group. E Dotplot showing the expression levels of Pdgfrβ in pericytes of each group. F Histogram showing the colocalization coefficients of endothelial cells and pericytes, these data were expressed as the mean ± SD, n = 4. G Immunofluorescence depicting the colocalization of endothelial cell (CD31, green) and pericytes (PDGFRβ, red) of each group (scale bar, 20 µm)