Fig. 7.

In depth profiling of monocytes. (a) UMAP visualization of total monocytes and subset identification in monocytes from treated and untreated groups; (b) Markers gene expression of monocyte subsets to reveal subsets by PhenoGraph clustering analysis; (c) Population differences of each subset of monocytes between treated and untreated groups; (d) Volcano plot diagram represents significant DEGs; e, f. DEGs with log2fold changes and gene ontology analysis of classical monocytes; g, h. DEGs with log2fold changes were observed with upregulated and downregulated genes, and gene ontology of non-classical monocytes; i. j. DEG analysis for intermediate monocytes visualized using log2fold changes, and gene ontology enrichment analysis. k. GSEA analysis to detect enrichment score for monocyte subsets