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. 2024 Dec 19;19:467. doi: 10.1186/s13023-024-03482-6

Fig. 2.

Fig. 2

Evaluation of randomization procedures for design optimization (ERDO) framework. This figure describes the ERDO framework, which is used to identify the best randomization procedure. The framework incorporates key aspects of the trial, including disease types, outcomes, and other relevant factors to find the best randomization procedure in the planning phase of the clinical trial