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. 2024 Dec 18;22:757. doi: 10.1186/s12951-024-03042-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 11 — a The preparation of AIE probes via a nanoprecipitation method. b Dynamic light scattering data of aqueous AIE probes. Inset: transmission electron microscopy image of water-dispersed AIE probes. c Fluorescence and absorption spectra of AIE probes. d NIR-II fluorescence imaging of the vessels and lymph nodes in cynomolgus monkey after intravenous injection of the AIE probes. (1) arm, (2) hand, (3) scalp vasculature, (4) an axillary lymph node marked by the red dotted line. e NIR-II fluorescence imaging of the deep axillary artery in a healthy adult cynomolgus monkey after intravenous injection of AIE probes. When epidermis was moved, the superficial vein was moved accordingly; however, the deep axillary artery remained stationary. Reproduced with permission from Tang et al. [121]