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. 2024 Dec 18;12:258. doi: 10.1186/s40168-024-01991-x

Table 2.

Examples of results and interpretations provided in the different reports

1 2 3 4 5 6
Health index Poor gut health — strongly altered microbiome Improvable health Average for gut health
Bacterial diversity index Good (based on Shannon index)

Values

Diversity — Shannon index: 6.08

Species richness: 277

Species evenness: 0.75

Average for the three parameters but interpreted as “Excellent”

Value = 250

Average

Value = 5.82

Average (based on Shannon index)

Unfavourable Good
Gut dysbiosis index High dysbiosis Small dysbiosis
Enterotypes Ruminococcus Bacteroides Bacteroides? Bacteroides
Inflammation

Anti-inflammatory (Lactobacillus ↑)

Pro-inflammatory (Proteobacteria ↑)

Excellent Average High = pro-inflammatory Average
(Value in % of relative abundance) Value Interpretation Value Interpretation Value Interpretation Value Interpretation Value Interpretation Value Interpretation
Bacillota 43.88 47.63 47.2 26.46 19 No value: the results are qualitative and only mention the presence or absence of identified bacteria
Bacteroidota 46.36 42.83 46.5 63.93 77
Actinobacteriota 2.27 1.77 2.3 3.72 2
Pseudomonata 2.39 0.93 2 3.05 1
Verrucomicrobiota 3.08 1.45 2 0.36 1
Examples of bacteria generally presented in the reports (value in % of relative abundance)
Akkermansia 0.53 Normal 0.34 High
Akkermansia muciniphila 2.44 High Normal 2.04 Optimal High Favourable
Bacteroides 29.16 Average 32.21 High 36.3 High
Bifidobacterium 1.19 High 0.53 Normal Optimal 1.68 High
Faecalibacterium 14.16 High 8.41 Low
Faecalibacterium prausnitzii 6.26 High High 5.7 and 0.22* Optimal Low Favourable

Presentation of some results obtained in the different reports (non-exhaustive list of examples). Conflicting results are obtained for the different indices evaluated (health index/diversity index/gut dysbiosis index), for the determination of enterotypes, for the estimation of inflammation and for the relative abundance of specific taxa (at the phyla or at the genera level)

*The company 3 reported 2 different relative abundances regarding Faecalibacterium prausnitzii for an unknown reason