Table 5.
Variables | Univariable analysis |
Multivariable analysis |
||
---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |
Δ RA reservoir strain, % | 0.93 (0.91–0.95) | <0.001 | 0.91 (0.86–0.96) | 0.004 |
Postoperative Echo Indices (Echo #2) | ||||
Postop pulmonary valve mean gradient | 1.04 (0.95–1.12) | 0.1 | ||
Pulmonary valve size, mm | 0.96 (0.85–1.08) | 0.4 | ||
Concomitant tricuspid valve repair | 1.14 (0.93–1.25) | 0.3 | ||
Concomitant RA maze operation | 1.28 (1.03–1.59) | 0.02 | ||
Postop RA pressure, mmHg | 1.06 (1.03–1.09) | <0.001 | 1.03 (1.01–1.06) | 0.03 |
Postop RV systolic pressure, mmHg |
1.04 (1.01–1.07) |
0.008 |
||
Preoperative Clinical Indices Demographics | ||||
Age, years | 1.06 (1.05–1.08) | <0.001 | 1.05 (0.98–1.12) | 0.2 |
Male sex | 0.65 (0.41–1.03) | 0.08 | 1.46 (0.94–1.76) | 0.4 |
Arrhythmia History | ||||
Preoperative atrial arrhythmias | 3.11 (2.04–4.75) | <0.001 | 2.76 (1.55–3.98) | 0.006 |
Surgical History | ||||
Age at TOF repair, years | 1.65 (0.86–2.04) | 0.3 | ||
Transannular patch repair | 1.97 (1.07–3.61) | 0.03 | ||
Prior systemic to pulmonary shun | 1.34 (0.73–2.18) | 0.5 | ||
PVR replacement prior to baseline | 1.12 (0.86–1.55) | 0.2 | ||
Comorbidities | ||||
Hypertension | 1.93 (1.21–3.08) | 0.005 | ||
Diabetes | 1.42 (0.82–1.46) | 0.2 | ||
Coronary artery diseas |
1.92 (1.01–3.65) |
0.04 |
||
Preoperative Echo Indices (Echo #1) | ||||
RA reservoir strain, % | 0.97 (0.95–0.99) | 0.02 | 0.96 (0.93–0.99) | 0.04 |
RA volume index, ml/m2 | 1.03 (1.02–1.04) | 0.003 | 1.02 (1.01–1.03) | 0.03 |
RA pressure, mmHg | 1.15 (1.09–1.21) | <0.001 | ||
RV global longitudinal strain*, % | 0.93 (0.84–1.03) | 0.2 | ||
RV systolic pressure, mmHg | 1.02 (1.02–1.03) | 0.004 | ||
≥Moderate tricuspid regurgitation | 2.32 (1.46–3.68) | <0.001 | ||
≥Moderate pulmonary regurgitation | 2.04 (0.83–4.11) | 0.4 | ||
Pulmonary valve mean gradient, mmHg | 1.01 (0.99–1.03) | 0.3 | ||
LA volume index, ml/m2 | 1.02 (1.00–1.04) | 0.08 | ||
LA reservoir strain, % | 0.96 (0.93–0.99) | 0.02 | ||
LV global longitudinal strain*, % |
0.97 (0.93–1.01) |
0.3 |
||
Preoperative CMRI Indices | ||||
RV end-diastolic volume index, ml/m2 | 0.96 (0.91–1.01) | 0.1 | ||
RV end-systolic volume index, ml/m2 | 0.95 (0.91–0.99) | 0.09 | ||
RV ejection fraction, % | 0.96 (0.92–1.00) | 0.1 |
Abbreviations: CMRI: cardiac magnetic resonance imaging; CI: confidence interval; HR: hazard ratio; LA: left atrium; LV: left ventricle; PVR: pulmonary valve replacement; RA: right atrium; RV: right ventricle; TOF: tetralogy of Fallot.
Footnote: * LV and RV global longitudinal strain were modeled as absolute values (i.e., without the negative sign). Note that only the covariates with statistically significant association with outcome are displayed in the multivariable model.