Table 1.

Relative severity of common mammalian cancer stem cells

Cancer Type	CSC Characteristics	Relative Severity	References
Breast Cancer	CD44 + /CD24-, ALDH1 +	High	[74, 75]
Colon Cancer	CD133 + , Lgr5 +	High	[76, 77]
Lung Cancer	CD133 + , CD44 +	High	[78–81]
Pancreatic Cancer	CD133 + , CD24 +	Very High	[82, 83]
Brain Cancer (Glioblastoma)	CD133 + , CD44 +	Very High	[69, 84–86]

The capacity of cancer stem cells (CSCs) to start and sustain tumor growth, evade therapy, and aid in metastasis is frequently linked to the severity of the tumors they support. However, the particular cancer type and the properties of the implicated CSCs can affect the relative severity of disease.