Table 1.
Effect of 1,25-(OH)2D3 on the number of TRAP +ve and ED1 +ve Bone Marrow Cells
Exp | Dose | Time | TRAP +ve BMC (#/mm2) | ED1 +ve BMC (#/mm2) | ||
Vehicle | 1,25-(OH)2D3 | Vehicle | 1,25-(OH)2D3 | |||
1 | 1 × 10 μg/kg | 2 d | 1.60 ± 0.41 | 16.37 ± 4.53* | 1.66 ± 0.33 | 16.67 ± 5.09* |
2 | 3 × 10 μg/kg | 2 d | 0.33 ± 0.16 | 0.44 ± 0.19 | 2.08 ± 0.45 | 4.58 ± 1.25* |
3 | 3 × 2 μg/kg | 4 d | 0.74 ± 0.13 | 0.67 ± 0.24 | 0.83 ± 0.33 | 1.46 ± 0.60 |
6 d | 0.63 ± 0.21 | 0.56 ± 0.19 | 1.25 ± 0.33 | 11.04 ± 4.00* | ||
9 d | 0.59 ± 0.27 | 0.59 ± 0.19 | 0.83 ± 0.30 | 1.36 ± 0.28 | ||
13 d | 0.56 ± 0.24 | 0.59 ± 0.24 | 1.36 ± 0.28 | 2.50 ± 1.18 | ||
17 d | 0.74 ± 0.19 | 0.78 ± 0.14 | 1.25 ± 0.33 | 2.92 ± 0.79* |
All values are means ± SE, *: P < 0.05.