Table 3.
CpG sites associated with current PTSD in the stratified analyses
| CpG | Position | Gene | β | SE | z | p-value |
|---|---|---|---|---|---|---|
| Stratified analysis for females | ||||||
| cg25691167 | chr7:19184961 | FERD3L | 0.09 | 0.03 | 5.48 | 4.24E-08 |
| Stratified analysis for males | ||||||
| cg05575921 | chr5:373378 | AHRR | -0.14 | 0.04 | -6.12 | 9.30E-10 |
| Stratified analysis for European ancestry | ||||||
| cg05575921 | chr5:373378 | AHRR | 0.05 | 0.02 | -6.85 | 7.24E-12 |
| cg21161138 | chr5:399360 | AHRR | -0.16 | 0.05 | -5.62 | 1.95E-08 |
| cg11256214 | chr12:110211642 | MGC14436 | 0.06 | 0.02 | 5.76 | 8.17E-09 |
| cg15977432 | chr19:56709655 | Intergenic | -0.05 | 0.02 | -5.46 | 4.68E-08 |
| cg04583842 | chr16:88103117 | BANP | 0.05 | 0.02 | 5.43 | 5.66E-08 |
| Stratified analysis for African ancestry | ||||||
| cg02003183 | chr14:103415882 | CDC42BPB | 0.11 | 0.04 | 5.48 | 4.26E-08 |
| Stratified analysis for civilian trauma | ||||||
| cg27541344* | chr14:99650422 | BCL11B | 0.02 | 0.04 | 5.39 | 7.21E-08 |
| Stratified analysis for military trauma | ||||||
| cg03329539 | chr2:233283329 | Intergenic | -0.03 | 0.01 | -5.36 | 8.53E-08 |
| cg21566642 | chr2:233284661 | Intergenic | -0.14 | 0.04 | -5.41 | 6.36E-08 |
| cg14753356 | chr6:30720108 | Intergenic | -0.04 | 0.02 | -5.47 | 4.53E-08 |
| cg05575921 | chr5:373378 | AHRR | -0.07 | 0.02 | -6.22 | 4.92E-10 |
| cg00774777* | chr11:76478902 | RP11-21L23.4 | 0.03 | 0.01 | 5.55 | 2.79E-08 |
Position is based on hg19. The sites that were also epigenome-wide significant (p < 9e-08) in the primary meta-analysis were shown in bold. CpGs specific to EPIC-array were indicated with an asterisk (*). β: Regression beta. SE: Standard error.