Fig. 1.

Establishment of Ccdc152^{full-locus del.} (FLD) mice and its effect on selenoprotein expression. (A) Schematic representation of the Ccdc152 genomic region. (B) Agarose gel electrophoresis of Ccdc152 editing in Ccdc152 FLD mice. (C–E) Expression of selenoproteins in the livers of Ccdc152 FLD mice, assessed using (C) qPCR, (D) western blotting, and (E) plasma SeP levels. (F) Quantification of the protein expression levels in (D) and (E). Data are shown as mean ± standard deviation (SD) (n = 3).